medication bottles image

$25

/month

3 mo. minimum required

medication bottles image

$25

/month

3 mo. minimum required

medication bottles image

$25

/month

3 mo. minimum required

Topical Spironolactone

Apostrophe

Topical spironolactone is a medication used to treat acne. Topical spironolactone is particularly effective for treating hormonal acne for everyone, regardless of sex, gender, or sensitivity to oral medications.$2525In stockApostrophe
4.57535
I loved Apostrophe because it was the easiest process to talk to my doctor, explain my issues, and get the prescription I needed to address them. Moreover, it was fast, and affordable.skin ReviewTopical Spironolactone5I could tell the Dr actually looked at my photos and read my response. Frankly it's just as good as showing up at a derm office in person.skin ReviewTopical Spironolactone5What an easy and affordable way to receive treatment! My care was not overlooked by convenience. I am beyond happy to have found Apostrophe!skin ReviewTopical Spironolactone5Alongside the Doxycycline prescribed, the Spironolactone + Clindamycin Formula has effectively reduced the inflammation of acne on my chin. While it is not yet gone, it is no longer swollen or bright red as it was to begin with.Spironolactone clindamycin formula ReviewTopical Spironolactone17354923214I put this on and instantly I could feel the anger and heat from my acne around my cheeks calm down. I felt less puffier too. I think I was a bit too excited at first and put too much that it dried my skin out so I alternate to every other day and it seems to be working really well. Im very sensitive to many other topicals but this one works so well on my hormonal acne.Spironolactone clindamycin formula ReviewTopical Spironolactone17319499214I've been suffering from hormonal acne around my jaw and neck for years. Oral spironolactone gave me side effects, so I stopped using it. Nothing else seemed to work. Once I discovered Apostrophe offered a topical solution, I was ecstatic! Had a little purging the first 2 weeks, but now I'm free and clear. Spironolactone clindamycin formula ReviewTopical Spironolactone17214919225This has become a game changer for me! Spironolactone clindamycin formula ReviewTopical Spironolactone17210599215I have been using this for little under a month so it seems to early to see any results. However, I am pleased overall with how easy and affordable it was to obtain this RX and feel good about moving forward with it.Spironolactone clindamycin formula ReviewTopical Spironolactone17114695223Hormonal birth control, retinol, ketoconazole, doxycycline, you name it I was on it. My acne went away on birth control so I knew it was an androgen issue, but I started having vitamin deficiency issues and got off it. The spironolactone was the magic ingredient Spironolactone clindamycin formula ReviewTopical Spironolactone16994635225Im definitely breaking out less, and my hormonal acne disappears a lot faster. Spironolactone clindamycin formula ReviewTopical Spironolactone16915975235I feel it has really helped with the hormonal acne I get around my period. It seems to really keep the acne under control when I have a breakout. Spironolactone clindamycin formula ReviewTopical Spironolactone16890919224My medication absorbs into my skin quickly, does not leave any discomfort, and has been effective at treating my symptoms. Spironolactone clindamycin formula ReviewTopical Spironolactone16873639225Strong sulfur smell is the only downside and it seems to fade quickly. On my skin, the formula is gentle. I haven't had any redness or "purging." Dramatic improvement about 2~weeks after incorporating it.Spironolactone clindamycin formula ReviewTopical Spironolactone16848583225I am so happy that I was prescribed topical spironolactone because there are no side effects to be concerned about and my skin has remained clear.Spironolactone clindamycin formula ReviewTopical Spironolactone16843399225I have been suffering from hormonal acne since I began having peri-menopause symptoms. I've tried so many things, and nothing seems to help. I read about topical spironolactone and thought I'd contact Apostrophe to find out more. My provider was prompt, informative, and thorough. I've only used the product for a short time, but my skin is improving. My only complaint would be the garlicky smell, but I can live with that if the product works!Spironolactone clindamycin formula ReviewTopical Spironolactone16839943225I have used this formula that was prescribed specifically for my needs and my skin and I'm already entering my second month using the product and my skin has cleared up tremendously! I had acne on my lower face on my chin and jaw area and tretinoin on its own was not working. Since combining these two ingredients together into a routine, my skin has changed drastically. My other main concern was that my skin was very oily and I am still waiting for that to subside a little. Maybe that will take a little more time.Spironolactone clindamycin formula ReviewTopical Spironolactone16831303224I have actually already noticed results. My confidence is coming back!!!!Spironolactone clindamycin formula ReviewTopical Spironolactone16831303225Slow to work - but still hopeful to see progress at the one month mark. No side-effects so glad not to deal with flaking or red skin. Easy application - I find it hard to believe I have enough in the bottle for three months using the directed amount but we'll see! The process has been super easy and I am appreciative of that! Stay tuned!Spironolactone clindamycin formula ReviewTopical Spironolactone16830439223I wish I did this earlier. I have not even been using this for a month and my skin is almost completely clear! I have some acne scars I will need to tackle next. I use this lotion at night in conjunction with a gentle Benzoyl Peroxide cleanser and ceramide moisturizer. DO THE THING. It is worth it. Spironolactone clindamycin formula ReviewTopical Spironolactone16707787225Clindamicin and spironolactone really seem to help my skin condition. I get clogged pores easily, and have some excess facial hair. This combo is very helpful for my skin. So happy to have found spironolactone in a skin lotion.Spironolactone clindamycin formula ReviewTopical Spironolactone16694827215I wanted to try this medication due to my chin acne and since using my skin has gotten better. Very happy !Spironolactone clindamycin formula ReviewTopical Spironolactone16683595225This product has been great to use! It isn't harsh on my skin, but has drastically helped to keep my acne cleared.Spironolactone clindamycin formula ReviewTopical Spironolactone16667143225Has completely cleared up my jawline acne and improved skin texture overall. Still having some sweat and heat reactive cysts from my Rosacea but those are improving.Spironolactone clindamycin formula ReviewTopical Spironolactone16629127225This has made a huge difference for me. I get a few spots here and there, but my skin is looking really good. I didn't even use the prescribed pills (to avoid so many potential side effects) and just used the cream. It's working well enough for now. So glad I found this!Spironolactone clindamycin formula ReviewTopical Spironolactone16617895225It did cause a little initial purge, but that's clearing up and my skin is adjusting just fineSpironolactone clindamycin formula ReviewTopical Spironolactone16603207225this is working okay, skin on my face is staying the same. a little drying Spironolactone clindamycin formula ReviewTopical Spironolactone16552231224It seems to be workin well! I wish I wouldve discovered apostrophe a long time ago!Spironolactone clindamycin formula ReviewTopical Spironolactone16501255225I've seen a bit of a difference with my skin so far. It's been a really stressful time, and I think my skin should be so much worse than it is right now. I have switched to using this during the day instead of at night to see if it helps control oil a bit, but I haven't really noticed much of a difference.Spironolactone clindamycin formula ReviewTopical Spironolactone16498663224I just started using this product and am seeing results, slowly but surely. Just takes patienceSpironolactone clindamycin formula ReviewTopical Spironolactone16448587224This is the final key to glowy skin! The oral spiro has been super helpful, but the topical has really made that final push!Spironolactone clindamycin formula ReviewTopical Spironolactone16427851225working well, but need to use slightly more than what is suggested to be able to cover the whole faceSpironolactone clindamycin formula ReviewTopical Spironolactone16331911214Had immediate results with these products! So very happy with how my skin looks! Thank you thank you!Spironolactone clindamycin formula ReviewTopical Spironolactone16318951225The topical helped with the pesky cystic bumps that hung around for awhile.Spironolactone clindamycin formula ReviewTopical Spironolactone16277479225This stuff smells like onions or food cooking. Not my favorite thing to put on my face. I've used a topical spironolactone from a custom compounding pharmacy in the past that had no smell so I wonder if this could be improved. In addition, my first shipment of this formula was super grainy. Customer service fixed it right away so I did not deduct any more stars from the rating. I feel that it has been helping clear up my acne. Spironolactone clindamycin formula ReviewTopical Spironolactone16276615224Has a weird smell to it but hoping it's working. Only have to use a tiny bit at nightSpironolactone clindamycin formula ReviewTopical Spironolactone16255879213I have struggled with my skin for so many years. This has really helped calm down my acne. My skin looks brighter, and my pores smaller. I have not had the huge breakouts I have had in the past. I am hopefully that I will continue to see these results...if so I will be a customer for life! Spironolactone clindamycin formula ReviewTopical Spironolactone16231687235I have been using spironolactone + clindamycin for almost a month and can say that it has stopped my cystic acne! Prior to using this formulation, I would get between 4-6 painful bumps along my chin line per month. I learned about Apostrophe from Cassandra Banksons Youtube channel and am so happy with the results I have seen in such a short time frame!Spironolactone clindamycin formula ReviewTopical Spironolactone16220455225Finding the right skincare regimen can be a lot of trial and error, especially when it comes to stubborn adult acne. Ive tried so many prescription products, many with mixed results. Some would be effective for a short period, while others seemed to cause more irritation and breakout. Thanks to this combination of medications, I have FINALLY found a solution to my cystic acne. Within a week of starting this duo, my cystic acne subsided. Deep, painful bumps disappeared from my jawline and the overall texture of my skin became smoother. Everyone responds different to medication, but if youre still struggling with acne or other issues, dont give up! It is so worth it when you find something that works for you (because something eventually will!)! Spironolactone clindamycin formula ReviewTopical Spironolactone16204039225

What is Topical Spironolactone?

Topical spironolactone is a medication used to treat acne. Topical spironolactone is particularly effective for treating hormonal acne for everyone, regardless of sex, gender, or sensitivity to oral medications.

topical medication pump
topical medication pump

What are the benefits of Topical Spironolactone?

Topical spironolactone reduces acne and decreases oily skin. It’s safe to use for all genders (unlike oral spironolactone which is typically not prescribed to cisgender or trans men for hormonal acne.)

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Read reviews of Apostrophe topical treatments below.

5.00/5 based on 5 reviews.
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1527 reviews
2/13/2025

Im three weeks into my Apostrophe journey. After several years of trying over the counter acne medication and wasting so much money, nothing ever really helped. I decided to try Apostrophe an I am currently on Doxycycline. Im slowly starting to notice my current acne clearing up and Im also starting to notice new acne era curing is very minimal. I know I havent been in the medication long but I am seeing improvements to my skin and more confidence in myself.

Ethan
2/13/2025
2/7/2025

I have been on Spironolactone before. With Tretinoin and Loestrin lo, this regimen works wonders for my hormonal acne. It takes two or three weeks to see improvement but if you are consistent, you will be very pleased.

Udonis
2/7/2025
2/7/2025

Switching to this medication to treat hormonal acne has been life changing. I haven't had any big breakouts and each day my skin gets clearer and smoother! I take it every night and do not have any side effects.

Kayla
2/7/2025
1/27/2025

I've used Spironolactone before so I know it works but it's been less than a month for me and I'm still waiting to see results. I know it takes a while so I must be patient and wait.

Maria Eduarda
1/27/2025
1/21/2025

I was suffering from hormonal acne during my pregnancy and Azelaic acid was the only ingredient I felt completely safe using to manage my hormonal breakouts. It took a few weeks to see a difference, like any acne treatment, but I'm not almost 20 weeks and my skin is looking so much clearer.

Melissa
1/21/2025
1/19/2025

It's my 3rd week of using this treatment and i see that my acne got worse (in a good way because it's a part of the treatment) we'll see on the upcoming months for the difference.

Kyle
1/19/2025
1/17/2025

This formula has helped heal my skin from perioral dermatitis. It has improved the texture of facial skin tremendously as well. I am thrilled with the results. Thank you Apostrophe.

Linda
1/17/2025
1/17/2025

This has worked super great for my skin and has cleared my acne and done wonders for my skin. I have noticed quite a bit of peeling and redness but its nothing compared to the results.

Kallia
1/17/2025
12/30/2024

I've been using the medication prescribed to me by Apostrophe for a few weeks now. I have hormonal acne which typically gets worse two weeks before my cycle, but recently I've been having more acne than usual. My hormonal acne has really cleared up since I've been using it, although I still get a small pimple here and there. Very impressed with how quickly it's working. Would recommend to anyone nervous about trying this company. At first I was nervous, but they have trained professionals who execute their job pretty professionally. Sorry for the longish review lol! I'm happy with my results so far.

Morgan
12/30/2024
12/29/2024

Doxycycline is easy to take and has effectively reduced the inflammation of my acne alongside the cream I was prescribed.

Carol
12/29/2024