Apostrophe Oral medication and topical medication bottles stacked on shapes
Apostrophe Oral medication and topical medication bottles stacked on shapes
Apostrophe Oral medication and topical medication bottles stacked on shapes

Topical and oral medications custom curated by your dermatology team.

Explore acne treatments

Apostrophe Custom Topical Formula

$75 for a 90 day supply

5.00/5 based on 0 reviews

This custom topical formula combines prescription-strength ingredients in a moisturizing lotion with aloe and vitamin e. Apostrophe topical medication blends seamlessly into your skincare routine - no more weird goopy aluminum tubes. All tailored to you by your expert dermatology team.

The ingredients

The fundamentals of your topical treatment

We don’t skimp on efficacy, ever. Apostrophe is rated the most effective acne treatment* by consumers for a reason. Apostrophe offers access to the widest range of prescription ingredients and strengths so we can create the formula that's perfect for your skin. From the most sensitive skin to the most severe acne, Apostrophe treatments have you covered.

*Based on a survey of 665 Apostrophe patients.

Acne treatment you'll want to use.

The smooth, creamy texture makes this prescription treatment blend seamlessly into your skincare routine, unlike goopy generics.

Oral Medications

$45-$90 for a 90 day supply

5.00/5 based on 0 reviews

Kickstart your acne treatment with oral medications. Apostrophe offers access to multiple kinds of antibiotic treatments that target acne-causing inflammation and hormonal acne treatments that can clear stubborn jawline acne in women.

Your clear skin
secret
weapon.

Oral medications are a powerful way to treat stubborn breakouts and hormonal acne. Think of them as your topical treatment’s partner in crime.

Antibiotics

These medications are typically short course treatments that help get your acne under control quicker. Your provider will only prescribe these if they feel you’ll get better results.

Learn more about antibiotics

Hormonal treatment

These treatments are for women who experience jawline breakouts that are caused by hormonal imbalances. Your provider will only prescribe this if they feel you’re a good candidate.

Learn more about hormonal treatments

Better, together.

Your treatment plan may contain several of these acne medications. Your dermatology provider will curate your customized treatment plan so you can get the best results.

“Acne has many different causes so medications work best in combination to fight acne from all angles. Topical treatments best target the root cause of acne, the clogged pore, while oral medications can quickly reduce inflammation to kickstart rapid improvement.”

Anne Allen, md

Real patients,
real results.

Read reviews of Apostrophe topical and oral medications below.

5.00/5 based on 5 reviews.
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Caret iconBlack upwards facing triangle to reference things above or scroll to the top of page.
1527 reviews
2/13/2025

Im three weeks into my Apostrophe journey. After several years of trying over the counter acne medication and wasting so much money, nothing ever really helped. I decided to try Apostrophe an I am currently on Doxycycline. Im slowly starting to notice my current acne clearing up and Im also starting to notice new acne era curing is very minimal. I know I havent been in the medication long but I am seeing improvements to my skin and more confidence in myself.

Ethan
2/13/2025
2/7/2025

I have been on Spironolactone before. With Tretinoin and Loestrin lo, this regimen works wonders for my hormonal acne. It takes two or three weeks to see improvement but if you are consistent, you will be very pleased.

Udonis
2/7/2025
2/7/2025

Switching to this medication to treat hormonal acne has been life changing. I haven't had any big breakouts and each day my skin gets clearer and smoother! I take it every night and do not have any side effects.

Kayla
2/7/2025
1/27/2025

I've used Spironolactone before so I know it works but it's been less than a month for me and I'm still waiting to see results. I know it takes a while so I must be patient and wait.

Maria Eduarda
1/27/2025
1/21/2025

I was suffering from hormonal acne during my pregnancy and Azelaic acid was the only ingredient I felt completely safe using to manage my hormonal breakouts. It took a few weeks to see a difference, like any acne treatment, but I'm not almost 20 weeks and my skin is looking so much clearer.

Melissa
1/21/2025
1/19/2025

It's my 3rd week of using this treatment and i see that my acne got worse (in a good way because it's a part of the treatment) we'll see on the upcoming months for the difference.

Kyle
1/19/2025
1/17/2025

This formula has helped heal my skin from perioral dermatitis. It has improved the texture of facial skin tremendously as well. I am thrilled with the results. Thank you Apostrophe.

Linda
1/17/2025
1/17/2025

This has worked super great for my skin and has cleared my acne and done wonders for my skin. I have noticed quite a bit of peeling and redness but its nothing compared to the results.

Kallia
1/17/2025
12/30/2024

I've been using the medication prescribed to me by Apostrophe for a few weeks now. I have hormonal acne which typically gets worse two weeks before my cycle, but recently I've been having more acne than usual. My hormonal acne has really cleared up since I've been using it, although I still get a small pimple here and there. Very impressed with how quickly it's working. Would recommend to anyone nervous about trying this company. At first I was nervous, but they have trained professionals who execute their job pretty professionally. Sorry for the longish review lol! I'm happy with my results so far.

Morgan
12/30/2024
12/29/2024

Doxycycline is easy to take and has effectively reduced the inflammation of my acne alongside the cream I was prescribed.

Carol
12/29/2024