British Journal of Dermatology

Comparative analysis of adverse drug reactions to tetracyclines: results of a French national survey and review of the literature.

British Journal of Dermatology

Minocycline was associated with more serious side effects than doxycycline and should not be considered first-line treatment for acne.

2012

https://www.ncbi.nlm.nih.gov/pubmed/22283782?dopt=Abstract

British Journal of Dermatology

Safety of long-term high-dose minocycline in the treatment of acne.

British Journal of Dermatology

Minocycline is a second-line antimicrobial acne for acne and doses up to 200mg/day is safe long-term when such doses are clinically necessary.

1996

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2133.1996.tb06972.x

Journal of Dermatological Treatment

Doxycycline versus minocycline in the treatment of acne vulgaris: A double-blind study.

Journal of Dermatological Treatment

Both doxycycline and minocycline significantly reduced acne when taken over 12 weeks and were found to be equally effective.

1989

https://www.tandfonline.com/doi/abs/10.3109/09546638909086681

Clinical and Experimental Dermatology

A comparison of doxycycline and minocycline in the treatment of acne vulgaris.

Clinical and Experimental Dermatology

In patients whose rosacea was successfully treated with tetracycline and metronidazole gel, the continued use of topical metronidazole alone caused fewer relapses than the vehicle.

1988

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2230.1988.tb00689.x

JAMA Dermatology

Efficacy of Minocycline Compared With Tetracycline in Treatment of Acne Vulgaris.

JAMA Dermatology

More patients treated with minocycline reached a non-inflammatory status for their acne than those treated with tetracycline.

1982

https://jamanetwork.com/journals/jamadermatology/article-abstract/543750