Expert Opinion on Pharmacotherapy

Benzoyl peroxide: a review of its current use in the treatment of acne vulgaris

Expert Opinion on Pharmacotherapy

Benzoyl peroxide is a first-line treatment for acne and its efficacy is enhanced when used in combination with topical retinoids or antibiotics.

2009

https://www.tandfonline.com/doi/abs/10.1517/14656560903277228

Dermatologica

Water-based versus alcohol-based benzoyl peroxide preparations in the treatment of acne vulgaris.

Dermatologica

Use of 5% benzoyl peroxide reduced acne by over 75% at 8 weeks in more than 70% of patients.

1986

https://www.ncbi.nlm.nih.gov/pubmed/2943613?dopt=Abstract

International Journal of Dermatology

Comparing 2.5%, 5%, and 10% benzoyl peroxide on inflammatory acne vulgaris.

International Journal of Dermatology

Benzoyl peroxide 2.5%, 5% and 10% formulations were equivalent at reducing inflammatory papules and pustules, but the 10% strength caused significantly more irritation.

1986

https://www.ncbi.nlm.nih.gov/pubmed/2948929?dopt=Abstract

British Journal of Dermatology

The short‐term effects of benzoyl peroxide lotion on the resolution of inflamed acne lesions.

British Journal of Dermatology

A 5% benzoyl peroxide lotion significantly reduced the number of inflamed acne lesions when used for only 5 days.

1982

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2133.1982.tb00906.x?sid=nlm%3Apubmed

Journal of Cutaneous Pathology

Studies on the Mechanism of Action of Topical Benzoyl Peroxide and Vitamin A Acid in Acne Vulgaris

Journal of Cutaneous Pathology

Benzoyl peroxide has a different mechanism of action than vitamin A or tetracycline

1974

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0560.1974.tb00628.x